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The CHROMacademy Essential Guide Webcast:
Translating to Hydrogen Carrier for GC – A Practical Perspective

Tuesday 18th February 2014, 16:00 GMT

The Essential Guide from LCGC’s CHROMacademy presents the definitive guide in translating your GC and GCMS methods from Helium to Hydrogen carrier gas.  In this session, Tony Taylor (Technical Director, Crawford Scientific) and Dr. Dawn Watson (Technical Expert, CHROMacademy, Crawford Scientific) explore the various reasons for translating GC methods to Hydrogen carrier including improved chromatography and faster throughput. The chromatographic benefits of adopting modern column geometries in conjunction with Hydrogen carrier gas will also be discussed.  We will highlight a very practical approach to method translation based on experience, and we will feature many tools and calculations which can be used to ease the translation experience, and maximize the benefits!  We will discuss regulatory challenges, such as, the need for method re-validation and approaches to verifying translated methods.

  • Key reasons and benefits of translating GC methods to Hydrogen Carrier
  • Direct translation or to improve speed and efficiency?
  • Tools and calculations to help with translation
  • What needs to be done – a practical checklist
  • Case study examples – avoiding pitfalls and maximizing benefits
  • Is method re-validation required?
 

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Who Should Attend:

  • Anyone who needs a template for method translation to Hydrogen carrier using improved method conditions and reduced dimension capillary columns
  • Anyone who would like to speed up their GC separations but are not sure how to translate the method variables or which column to use
  • Anyone who pays too much for helium cylinders!
   


Find out more about this Month's Essential Guide Webcast »

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In this session, Tony Taylor (Technical Director, Crawford Scientific) and Dr. Dawn Watson (Technical Expert, CHROMacademy, Crawford Scientific) explore the various reasons for translating GC methods to Hydrogen carrier including improved chromatography and faster throughput. The chromatographic benefits of adopting modern column geometries in conjunction with Hydrogen carrier gas will also be discussed. We will highlight a very practical approach to method translation based on experience, and we will feature many tools and calculations which can be used to ease the translation experience, and maximize the benefits! We will discuss regulatory challenges, such as, the need for method re-validation and approaches to verifying translated methods.

Tony Taylor
Technical Director
Crawford Scientific

Dr. Dawn Watson
Technical Specialist
Crawford Scientific

Key Learning Objectives:

  • Identify the reasons and benefits for method translation in GC
  • Discuss how to select columns for improving separations and reducing analysis time
  • What factors need to be considered when translating to smaller column i.d.; higher carrier velocity or the use of hydrogen as carrier gas
  • A logical approach to translating method variables and instrument hardware
  • Tools and calculations to translate carrier gases
  • Practical case studies of method translation
  • Perspectives on method re-validation and verification