| 1. | Molecular Weight Determination of LMWH SEC/MALS vs. SEC/ UV-RI
Low-molecular-weight heparins (LMWHs) are obtained by fractionation or depolymerization of natural
heparins. They are defined as having a... |
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| 2. | Maximize Zero Grade Air Purity
When running a gas chromatograph (GC) with a flame ionization detector (FID) the choice of purity of
the air used is extremely important to the... |
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| 3. | Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from
Lean, Fat, and Obese Rats
This exploratory research demonstrates the applicability of comprehensive two-dimensional gas
chromatography (GCxGC), coupled with time-of-flight... |
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| 4. | Increasing LC–MS-MS Sample Throughput Using the Transcend TLX-2 System and Multiplexing for
Research
Learn how to gain a significant increase – 393% – in sample throughput
compared to standard HPLC methods in bioanalytical research... |
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| 5. | Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from
Lean, Fat, and Obese Rats
This exploratory research demonstrates the applicability of comprehensive two-dimensional gas
chromatography (GCxGC), coupled with time-of-flight... |
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| 6. | Optimizing Gel Permeation Chromatography (GPC) Using Economical, Quality Phenogel™
Columns
Gel permeation chromatography (GPC) is principally used to separate polymers and organic molecules
based on their size. Column, mobile phase, and... |
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| 7. | Identification & Quantification of Wine Impurities by GC–MS
By identifying maturation tracers and molecules commonly responsible for taste defects in wine,
GC–MS augments expert opinion with... |
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| 8. | Fast Analysis of VOCs in Polystyrene Using a Capillary Backflush GC System
Residual organic solvents in food packaging materials are a problem because of the implications to
food safety. Polystyrene is widely used in... |
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| 9. | Using the CIA Advantage for Automated Cryogen-Free Analysis of Canister Air and Gas
The CIA Advantage™ is an advanced system for the automated analysis of VOCs in air or
gas sampled using canisters. This application note... |
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| 10. | Structural Elucidation of Alkylamines in Process Streams by GC–MS-MS
In order to monitor the production of amines, GC–MS-MS analysis was performed to
identify the constituents of the raw product. This... |
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| 11. | Application of TargetView GC-MS Software for the Identification of Chemical Warfare Agents in Complex
Real-World Samples
This application note describes the use of TargetView™ GC-MS software to detect and
identify chemical warfare agents (CWAs) in complex... |
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| 12. | Characterization of a Cannabinomimetic Compound in Synthetic Cannabis by Gas Chromatography-High Resolution
Time of Flight Mass Spectrometry (GC-HRT)
The Pegasus® GC-HRT is a valuable tool for crime labs to effectively characterize new and
emerging synthetic cannabinoid compounds. The... |
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| 13. | Single Column GC-MS Analysis of the 12 Polychlorinated Biphenyls (PCBs) Designated as Toxic by the World
Health Organization (WHO)
Simplified GC-MS analysis by providing resolution of all 12 toxic congeners using one column: the
Zebron ZB-5ms GC column. The phase utilizes a... |
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| 14. | Using an In-house H2 Generator to Replace He Carrier Gas for GC
H2 is commonly used as GC carrier gas as the cost of He is increasing and its availability is
decreasing. In addition to the cost and... |
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| 15. | Trace Oxygenated Hydrocarbons in Liquid Hydrocarbon Streams by Multidimensional GC
Accurate determination of trace oxygenated hydrocarbons in liquid hydrocarbon streams plays an
important role in process design and operation.... |
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| 16. | Confirmation and Quantitatioin of Opiates in Urine
Structural similarities of opiate metabolites introduce challenges to the accurate separation,
confirmation and quantitation of these substances.... |
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| 17. | Evaluation of a New Analytical Trap for GRO Analysis
This study will evaluate a new analytical trap that is designed by Teledyne Tekmar. The packing
material in this new trap improves the recovery... |
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| 18. | Saccharide and Polysaccharide Analysis
The new SUPREMA column, with a reduced particle size of 5 µm, offers a significant
improvement in performance compared to 10 µm... |
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| 19. | Wyatt - Agarose Characterization with high temperature
This note describes the characterization of agarose by size-exclusion chromatography (SEC) and
multi-angle light scattering (MALS) at an elevated... |
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| 20. | Detection and Identification of Gulf Oil Dispersants (COREXIT® 9527 and 9500) by GC-MS and
LC-MS-MS
In an effort to contain the largest oil spill in United States history, nearly a million gallons of
dispersant have been pumped into the Gulf of... |
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| 21. | Analysis of 258 Pesticides in Vegetable Matrix
A method for analysis of 258 pesticides has been developed on Scion TQ triple quadrupole mass
spectrometer. The method setup is streamlined with... |
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| 22. | Bath Salt Characterization Using a Headspace Analyzer and GC-MS
With chemists engineering new “designer drugs” everyday, law enforcement
and regulatory bodies need testing to quickly and accurately... |
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| 23. | Lower Detection Limits of Volatile Nitrosamines in Tobacco by GC-MS-MS
Volatile nitrosamines (VNA) are a class of compounds that are known to pose significant health risks
in tobacco. This application note describes... |
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| 24. | Organophosphorus Pesticides in Apple Matrix by GC-MS-FPD
The Agilent J&W DB-35ms Ultra Inert column effectively resolved the analytes of interest
producing excellent peak shape for even the more... |
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| 25. | Analyze More Semivolatiles Using Split Injection
Semivolatiles are typically analyzed using splitless injection, but this approach results in slow
analysis times and significant variability. In... |
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| 26. | Analysis of an Expanded Panel of Sympathomimetic Amines in Urine
A method for the confirmation and quantification of sympathomimetic amines in human urine was
developed using the Thermo Scientific ISQ Single... |
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| 27. | Unravelling the Complexity of Fragrances in HPC* Products Using TruTOF GC–TOF-MS with
Automated Data Deconvolution
The composition and analysis of fragrance components in home and personal care (HPC) products is very
complex and unquestionably time consuming. |
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| 28. | Tracking Flavours in White Wine and Coffee Flavour Profiling of Food Samples with SPME-GC–MS
and On-column Injection
SPME-GC–MS with on-column injection can be successfully employed for flavour profiling
of food samples. The on-column injector of the... |
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| 29. | Analysis of 17-Pesticide Residues in Apple Using Agilent SampliQ QuEChERS EN Kits and Agilent
J&W Ultra Inert columns by GC–MS
The QuEChERS method for pesticide analysis was first introduced by USDA scientists in 2003. The EN
method 15662:2007 is a European variation to... |
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| 30. | Multiresidue Pesticide Analysis in Onion by a Modified QuEChERS Extraction and Ion Trap GC–MSn
Analysis
Most recently formulated pesticides are smaller in molecular weight and designed to break down rapidly
in the environment. |
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| 31. | Flavour and Fragrance Analysis Easy Heart-cut MDGC with Mass Spectrometric Detection in 1st and 2nd
Dimension
This article reports on multidimensional gas chromatography using a multi-Deans switch that allows
easy heart-cutting. |
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| 32. | The Use of Subtle Differences in Selectivity to Improve Separation of Structurally Diverse Analytes
The separation of structurally diverse analytes is often complicated by chance coelutions with other
analytes or with matrix related compounds.... |
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| 33. | New Innovations for EPA 8260 Analysis
Over the past 15 years, little has changed for the commercial environmental laboratory's ability to
automate U.S. EPA Method 8260 for water and... |
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| 34. | Can You Use Nitrogen as an Alternate Purge Gas for Analysis of Volatile Organic Compounds (VOCs)?
Most U.S. Environmental Protection Agency (U.S. EPA) methods for analysis of volatile organic
compounds (VOCs) specify purging with helium for 11... |
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| 35. | Chlorinated Solvents and Disinfection By-product Analysis Using Agilent J&W HP-1ms Ultra Inert
and DB-1301 Capillary GC Columns
Trace-level chlorinated hydrocarbon analyses using methods such as U.S. EPA Method 551.1 are important
tools for assessing organochlorine... |
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| 36. | Flexible Fused Silica Capillary: A Discussion of Strength
Synthetic fused silica capillary tubing is a vital component in many scientific techniques. The
general perception is that most laboratory glass... |
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| 37. | Glycerin in Biodiesel by Capillary GC Analysis
Biodiesel is much in the news today as an alternate fuel source that is safe and nontoxic. It is
renewable, via farming and recycling, and is... |
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| 38. | Analysing Pesticides in Rice Using GC–MS–MS and QuEChERS Sample
Preparation
Confirmation and quantification of pesticide residues in rice can be accomplished with low detection
limits and high productivity by using gas... |
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| 39. | Diversity of Methodologies for Melamine Analysis in Dairy Products
Recently, melamine has been reported in infant formula as the prime culprit for protein adulteration
in dairy products. This paper will present... |
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| 40. | Trace Level Analysis of Melamine in Milk Products on 7890A/5975C Using a New Agilent J&W DB-5ms
Ultra Inert Column and SamliQ SCX Cartridges
GC–MS method is presented for the quantitative determination and confirmation of
melamine residues in milk products. The milk sample was... |
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| 41. | Contract Laboratory Programme (CLP) Pesticide Analysis with 0.18 mm i.d. High-Efficiency GC Columns Using
Helium Carrier Gas
Contract laboratory programme (CLP) pesticide analysis is demonstrated using a high-efficiency GC
column (20 m × 0.18 mm i.d.... |
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| 42. | Comprehensive GC3GC(qMS) Qualitative and Quantitative Analysis of PCBs using EI and NCI Mode with a Rapid
Scanning Quadrupole Mass Spectrometer
Comprehensive GC×GC, invented by J. Phillips in 1989,1 has experienced
rapidly increasing interest in the last years. The original... |
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| 43. | In-House Generation of Hydrogen for Gas Chromatography
Hydrogen, commonly used as a carrier gas instead of Helium for gas chromatography (GC) can be supplied
via cylinders or by the electrolysis of... |
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| 44. | Analysis of Volatile Organic Compounds in Air by Thermal Desorption
The Clean Air Act (CAA) (1) provides the U.S. Environmental Protection Agency authority to enforce
regulations limiting emissions of volatile... |
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| 45. | Case Studies: Improved Productivity with Fast GC Accessories
Thermal agility is a term that describes the ability of an oven to heat up and cool down. Both steps
comprise the complete cycle time which, in... |
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| 46. | Polycyclic Aromatic Hydrocarbon (PAH) Analysis Using an Agilent J&W DB-5ms Ultra Inert Capillary
GC Column
Trace-and ultra trace-level polycyclic aromatic hydrocarbon (PAH) analyses are important tools for
accessing environmental quality and foodstuff... |
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| 47. | GC–MS Screening for Melamine Adulteration in Baby Formula and Dairy Products
Melamine is an industrial chemical with a high nitrogen content that can cause kidney stones and lead
to renal failure. In some instances,... |
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| 48. | Analysis of PCBs in Food and Biological Samples Using GC-Triple Quadrupole MS–MS
This application details a fast, reliable and highly selective trace-level screening method for the
quantification of polychlorinated biphenyls... |
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| 49. | Polybrominated Diphenyl Ether (PBDE) Analysis Using an Agilent J&W DB-5ms Ultra Inert GC
Column
Polybrominated diphenyl ether (PBDE) analyses are important tools for understanding food supply and
environmental quality worldwide. In this... |
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| 50. | The Analysis of Sulphur Components in Various LPGs
The low level analysis of sulphur containing components such as H2S, COS and mercaptanes is
challenging. First of all the system has to be inert;... |
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| 51. | The Benefits of Incorporating GC/QQQ into Pesticide Analysis Methods
Pesticide residue analysis is a complex task because the analyst often has to search for hundreds of
compounds in a wide variety of matrices. As... |
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| 52. | Analysis of Deoxynivalenol in Beer
Mycotoxins, toxic secondary metabolites of several fungal species, represent food safety issues of
high concern. Deoxynivalenol, the most... |
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| 53. | Real-Time Response to Bacteria Infection of Bioethanol Fermentation Using a Short Rezex™ ROA
Column
Political priorities as well as economic interests have fueled a dramatic growth in the biofuel
industry, due much in part to research funding... |
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| 54. | Synthetic Fused Silica Capillary Tubing: A Discussion of Diffusion
Synthetic fused silica capillary tubing is commonly used as the preferred substrate for
chromatographic separation columns. In limited instances... |
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| 55. | Agilent J&W Ultra Inert GC Columns: A New Tool to Battle Challenging Active Analytes
QC test probes serve a vital function in ensuring the reproducibility of modern GC columns. These
probes ensure that the columns have been... |
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| 56. | Performance Gains Using Hydrogen Carrier Gas in Refinery Gas Analysis
Escalating costs and increasing demands for helium, coupled with diminishing helium supply, have given
rise to the investigation and use of... |
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| 57. | Semivolatile Analysis Using an Inertness-Performance-Tested Agilent J&W DB-5ms Ultra Inert
Column
Semivolatile analyses using methods similar to US EPA method 8270 (1) are important in environmental
laboratories worldwide. A number of acidic... |
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| 58. | Meeting the Updated Requirements for the Determination of Residual Solvents in Pharmaceutical
Materials
The European Pharmacopoeia (EP) method 2.4.24 is the reference method for the determination of
residual solvents in pharmaceutical materials.... |
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| 59. | New Generation of GC/High Resolution TOF-MS: APCI/APLI Source for Increased Flexibility
A new APCI/APLI source enables a high resolution TOF-MS to be coupled on LC and GC, thus increasing
flexibility and performance of TOF-MS in... |
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| 60. | Fast Multi-Residue Pesticide Analysis Using Triple Quadrupole GC–MS–MS
H-SRM provides excellent selectivity for accurate identification and quantification of pesticides in
matrix, demonstrating high productivity for... |
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| 61. | Reducing Matrix Impact on Trace Analysis with GC–MS: A Simple Capillary Flow Technology
"Tee" for Improved Backflush Efficiency
Capillary flow technology (CFT) devices are microfluidic components that extend capillary GC
capabilities through simple and robust connections... |
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| 62. | Biodiesel Patterns Reflect Quality
In the last few years, biofuels have become well established as an independent source of energy in the
industrial countries. The percentage of... |
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| 63. | Agilent J&W Ultra Inert GC Columns: A New Tool to Battle Challenging Active Analytes
QC test probes serve a vital function in ensuring the reproducibility of modern GC columns. These
probes ensure that the columns have been... |
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| 64. | Fast Bioethanol Analysis Using the New Zebron ZB-Bioethanol GC Column
The Zebron ZB-Bioethanol GC column reduces fuel ethanol analysis time to less than 8 minutes, while
providing complete resolution of methanol and... |
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| 65. | Semivolatile Analysis Using an Inertness-Performance-Tested Agilent J&W DB-5ms Ultra Inert
Column
Semivolatile analyses using methods similar to US EPA method 82701 are important in environmental
laboratories worldwide. A number of acidic... |
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| 66. | Determination of Organic Compounds in Drinking Water Using Atlantic SPE Disks for EPA Method 525.2
EPA Method 525.2 describes the procedure to determine low ppb levels of semi-volatile organic material
in drinking water using solid phase... |
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| 67. | Fast Bioethanol Analysis Following ASTM Method D 5501 Using the New
Zebronâ„¢ ZB-Bioethanol GC Column
The Zebron ZB-Bioethanol GC column reduces fuel ethanol analysis time to less than 8 min, while
providing complete resolution of methanol and... |
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| 68. | Flexible Fused Silica Capillary: A Review of Internal Surface Chemistry
Synthetic fused silica capillary tubing has proven to be a vital component in many separation science
techniques. Recently, it has expanded to... |
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| 69. | Techniques for Reducing Purge-and-Trap Cycle Times in VOC Analysis
The purge-and-trap (P&T) technique for analysis of volatile organic compounds (VOCs) was
pioneered in the 1970s at the United States... |
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| 70. | Rapid Analysis of Flavors and Fragrances Using High-Efficiency GC Columns
There are many misconceptions about what it means to perform fast gas chromatography (GC) and what the
term fast GC implies. Fast GC is often... |
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| 71. | Automated Sample Cleanup of Olive Oil
Gel permeation chromatography (GPC) has been used as an effective cleanup procedure for removing high
molecular weight interfering molecules such... |
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| 72. | Method 6040D, Odors in Drinking Water, Using SPME on the Supelco SLB-5ms Capillary Column
A method for trace odor components, isopropyl-methoxypyrazine (IPMP), isobutyl-methoxypyrazine (IBMP),
methylisoborneol (MIB), and geosmin in... |
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| 73. | New Tool Ensures Painless GC Column Installation
Proper column installation is critical for precise and optimal functioning of any gas chromatography
(GC) system. Yet errors in this seemingly... |
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| 74. | Determination of Geosmin and 2-MIB in Drinking Water by SPME-PTV-GC–MS
This application describes the analysis of two key taste and odour compounds in drinking water using
solid-phase microextraction and gas... |
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| 75. | What Irritates the Skin? Quantitative Determination of Potential Allergens in Cosmetic Products Using Direct
Thermal Desorption (DMI) and Comprehensive GC3GC(qMS)
Quantitative determination of potential allergen compounds as defined by the International Fragrance
Association (IFRA) in cosmetics (perfumes,... |
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| 76. | GC–MS Determination of Phthalate Concentration in Plastic Toys
Phthalates are added to plastics to increase flexibility. Recently, concerns have been raised over the
effect of phthalate exposure from plastic... |
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| 77. | Comprehensive 2D GC for Achieving Nitrogen Speciation in Middle Distillates
|
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| 78. | Analysis of Wastewater for Volatile (Purgeable) Organics by GC–MS
A comprehensive approach to the analysis of volatile (purgeable) organics in waste and wastewater
allows straightforward achievement of method... |
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| 79. | Tips to Meeting the Criteria of the Upcoming Revised USP Monograph <467>: Residual
Solvents
This July, the USP is adopting a modified version of the ICH Quality-3C methodology. This revision
provides a risk-based approach to residual... |
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| 80. | Fast, Accurate Semivolatiles Analysis Using Rxi-5Sil MS Capillary GC Columns
|
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| 81. | Analysis of Total Glycerin in Biodiesel Using an MXT-Biodiesel TG Column with a Built-in Retention
Gap
|
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| 82. | New Tool Ensures Painless GC Column Installation
|
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| 83. | Capillary Tubing: Uniquely Shaped Internal and External Geometries
|
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| 84. | Is Bottled Nitrogen a Greenhouse Gas?
|
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| 85. | Reliable Analysis of Glycerin in Biodiesel Using a High-Temperature Non-Metal GC Column
|
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| 86. | Comprehensive 2D GC for Achieving Nitrogen Speciation in Middle Distillates
|
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| 87. | Analysis of Essential Oil Enantiomers by Chiral GCxGC-TOFMS
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| 88. | High-Efficiency FAME Analysis Using Capillary GC
Allen K. Vickers, Agilent Technologies |
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| 89. | A Novel Method for the High-Speed Determination of Fuel Diluents in Lubricating Oils
Timothy Ruppel, Gerald Hall, and Andrew Tipler, PerkinElmer, Inc. |
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| 90. | Fused Silica Capillary Tubing: A Review of Capillary External Coatings
Drew Stasiak and Joe Macomber, Polymicro Technologies |
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| 91. | A "Solid" Alternative for Analyzing Oxygenated Hydrocarbons Agilent's New Capillary GC PLOT
Column
Allen K. Vickers, Agilent Technologies |
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| 92. | Determination of Free and Total Glycerin in B-100 Biodiesel via Method ASTM D6584
James Chang, Robert Biniakewitz, and Gail Harkey, Thermo Fisher Scientific Inc. |
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| 93. | Reliable Analysis of Glycerin in Biodiesel Using a Non-Metal GC Column
Kory Kelly, Sky Countryman, and Ngoc Nguyen, Phenomenex, Inc. |
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| 94. | High-Efficiency FAME Analysis Using Capillary GC
Most authorities currently agree that saturated fatty acids are undesirable in one's diet and that
hydrogenated fats can also be unhealthy.... |
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| 95. | Practical Fast Gas Chromatography Using Smaller Diameter Columns and Hydrogen Carrier Gas
Several GC runs were made with DB-XLB columns using the Contract Laboratory Program (CLP) pesticide
analytes of 22 compounds and optimized method... |
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| 96. | Determination of Free and Total Glycerine in Pure Biodiesel (B100) by Gas Chromatography in Compliance with
EN14105
|
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| 97. | A "Solid" Alternative for Analysing Oxygenated Hydrocarbons — Agilent's New
Capillary GC PLOT Column
PLOT columns are often used in GC analyses when it is necessary or desirable to retain one class of
solutes in favour of other solutes that have... |
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| 98. | GC Analysis of Biodiesel Using a High Temperature Carborane-Modified Siloxane Phase Column
The manufacture of biodiesel involves the conversion of triglycerides (usually from vegetable oils) in
the presence of an alcohol, to the... |
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| 99. | Biodiesel Analyser Determines the Quality of Fatty Acid Methyl Esters (FAME) Blending Stock for Diesel
Fuel
AC Analytical Controls developed a new chromatographic solution that complies with all ASTM
& EN chromatographic test methods listed in biodiesel... |
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| 100. | A Novel Method for the High-Speed Determination of Fuel Diluents in Lubricating Oils
The performance of lubricating oil is significantly degraded by the presence of fuel contaminants such
as gasoline and diesel. Recycled oil is... |
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