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Used by over 35,000 chromatographers worldwide, CHROMacademy will help increase your knowledge, efficiency and productivity in the lab. With a vast library of high-quality animated and interactive e-learning topics, webcasts and tutorials we can help you refresh your chromatography skills or learn something completely new.
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  Packed with practical information that will help improve your skills and employability.


 
HPLC Gradient Elution My LC-MS isn’t behaving Infrared Spectroscopy Quiz Headspace GC
HPLC Gradient Elution – Baseline Drift My LC-MS isn’t behaving!
Where do I start?
Infrared Spectroscopy Pub Quiz
The Why, What, and How of Headspace GC
The CHROMacademy technical team was recently posed with the question of the causes of baseline drift in gradient HPLC. 
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Instrument manufacturers try to convince us that mass spec is just another detector. Most of us who work with LC-MS know that’s simply not the case – they can be maintenance intensive, unforgiving and generate complex information. When they’re not working it can be difficult to work out exactly where the problem lies. 
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How Much do You Know About Infrared Spectroscopy?
Find out with our quick quiz !
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Headspace sampling is excellent for the qualitative or quantitative analysis of volatile species in samples that can be efficiently partitioned into the headspace gas volume from either a liquid or solid matrix.  It is also a good technique for the analysis of samples where the entire sample should not be injected into the GC instrument (i.e. dirty samples).   
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Troubleshooting Variable Peak Height/Area in HPLC 10 Ways to Break Your LC-MS GC Stationary Phases 10 Common GC Mistakes
Troubleshooting Variable Peak Height/Area in HPLC
10 Ways to Break Your LC-MS
Quick Guide to Capillary GC Stationary Phases
10 Common GC Mistakes
When a problem with an HPLC separation occurs it is often best to take a step back and think about what may have caused the problem... 
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If there’s one mantra that’s essential for an LC (or GC)-MS operator it’s “contamination, contamination, contamination”.
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The single biggest factor in obtaining a suitable GC separation is the choice of column chemistry. Get it right and everything moves smoothly, get it wrong and you’ll waste a lot of time trying to optimize all the wrong parameters.
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  1. Not Taking Enough Care at the Inlet
  2. Turning the oven on before the carrier gas
  3. Not programming in column dimensions
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Troubleshooting retention time variability in HPLC Troubleshooting retention time variability in HPLC Troubleshooting retention time variability in HPLC Troubleshooting retention time variability in HPLC
I only ever need C18…don’t I? You need a fancy new UHPLC system to run Fast HPLC... don’t you? GC column selection quiz 10 good reasons for adding a mass spectrometer to my UV-HPLC?
We’re probably all guilty at some point of starting all new method development projects with our favourite and most trusted C18 column installed on the system. Whilst our old favourite C18 may perform an adequate job it may lead to a lot more work during method development or a method that it is non-optimal.  more » Is it possible to substantially reduce runtimes using a standard HPLC system (400 bar maximum pressure) and conventional column technology? 
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Find out just how much you know about GC columns and GC column selection.  Take the quiz » 1) Get molecular weight information on a peak...
2) Better selectivity...
3) Better sensitivity...
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