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Introduction

Microextraction techniques have been known since the mid-1990’s and have continued to gain popularity.  The primary aims of any sample preparation technique is to provide clean samples and enrich analytes to reduce limits of detection (LOD).  The sample preparation technique should ideally be cheap, easy, fast, and compatible with a range of analytical instrumentation.

The miniaturization of liquid phase extraction techniques fulfills many of these criteria and, hence, their development and application has been prolific since their inception. 

Liquid phase microextractions are performed using a small amount of water-immiscible organic solvent (or in the case of headspace extractions water-miscible solvents can be used) to extract analytes from an aqueous sample. 

Liquid phase microextraction techniques include single drop microextraction (SDME), dispersive liquid-liquid microextraction (DLLME), and hollow-fiber microextraction (HF-LPME).1

 

 

 

 

 

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