| 1. | Determination of Polycyclic Aromatic Hydrocarbons(PAHs) in Seafood Using GC–MS
This method is used for the determination of polycyclic aromatic hydrocarbons (PAHs), polychlorinated
biphenyls (PCBs), and polybrominated... |
|
| 2. | Extraction of Antioxidants from High Density Polyethylene (HDPE) by Pressurized Liquid Extraction
(PLE)
Plastics and other polymers are used in a wide spectrum of applications from industrial usage to
packaging, including the packaging of food and... |
|
| 3. | One-Step Extraction and Concentration for Identifying Pharmaceuticals and Personal Care Products in Water,
Biosolids and Solids
The scope of human exposure to pharmaceuticals and personal care products (PPCPs) from the environment
is complicated and increased monitoring is... |
|
| 4. | Oil and Grease Analysis by EPA Method 1664 Hexane Extractable Materials
Rapid extraction of 1 L in 2 min; capacity of 3000 mg! Even with the dirtiest water samples, the UCT
C18 extraction cartridge ECUNIOGXF, designed... |
|
| 5. | Simplified Extraction and Rapid LC–MS-MS Analysis of Synthetic Cannabinoids from Urine Using
Strata™-X-Drug N Solid Phase Extraction (SPE) and Kinetex 2.6 µm PFP Core-Shell
HPLC/UHPLC Columns
The goal of this study was to develop an LC-MS-MS method for urinary synthetic cannabinoids for use in
confirmational analysis. Because of the... |
|
| 6. | Automated Solid Phase Extraction and Concentration for EPA Method 525.2 in Drinking Water
The following note was developed to demonstrate the benefits of automating EPA Method 525.2 using SPE
cartridges, the FMS PowerPrep™ SPE,... |
|
| 7. | Ion Exchange Sorbents for Metals Extraction
UCT, Inc. offers a full line of Enviro-Clean® ion exchange sorbents for trace metals
extraction in environmental samples and other matrices.... |
|
| 8. | Extracting Organochlorine Pesticides from Water With Atlantic™ HLB-M Disks (EPA Method
8081)
The purpose of this application note is to establish a solid phase extraction (SPE) procedure to
streamline the sample preparation process for... |
|
| 9. | Automated Solid Phase Extraction and Concentration of PAHs in Water
Analytically, PAHs present challenges for testing labs. Their volatile nature can make them
problematic to extract without loss using manual... |
|
| 10. | A Simple Approach to Fast and Practical Solid Phase Extraction (SPE) Method Development
Solid phase extraction is an effective technique for cleaning up and concentrating samples. In the
following application note we outline a simple... |
|
| 11. | Determining DROs With Automated SPE
Method detection limits for EPA Method 8015 Diesel Range Organics using fully automated extraction and
concentration equipment (SPE-DEX 4790... |
|
| 12. | QuEChERS-Based LC-MS-MS Method for Multiresidue Pesticide Analysis in Fruits and Vegetables
A high-throughput QuEChERS method (LC-MS-MS) is described for orange, peach, spinach and ginseng
covering 191 carbamates, polar organophosphates,... |
|
| 13. | Extracting Organochlorine Pesticides from Water with Atlantic–HLB-M Disks (EPA Method
8081)
The purpose of this application note is to establish a solid phase extraction (SPE) procedure to
streamline the sample preparation process for... |
|
| 14. | Modified QuEChERS Procedure for the Analysis of Bisphenol A in Canned Food Products
The concentration of bisphenol monomer in various pigmented and nonpigmented food products can be
rapidly determined using a modified QuEChERS... |
|
| 15. | Automated Solid Phase Extraction and Concentration for the Determination of Nitrosamines in Drinking
Water
Nitrosamines are a group of chemical compounds regulated due to their carcinogenic characteristics.
Nitrosamines have many sources including... |
|
| 16. | Rapid Determination of DNPH Derivatized Carbonyl Compounds
In this application note, six low molecular weight carbonyls are first derivatized and then separated
by UHPLC on a BlueOrchid C18 A column. The... |
|
| 17. | BenchTOF-dx and TargetView ? High-Definition, Versatile Technologies for the Identification of TO-15/TO-17
?Air Toxics?
This Note shows that GC/TOF MS (BenchTOF-dx?) and TargetView? software are excellent tools for testing
a complex semi-rural air sample for the... |
|
| 18. | Determination of 1,4-Dioxane in Drinking Water by Solid Phase Extraction (SPE) and GC-MS with Selected Ion
Monitoring (SIM)* EPA Method 522
The challenging analysis of highly water soluble 1,4-dioxane has been overcome using UCT
ENVIRO-CLEAN® SPE activated carbon cartridge... |
|
| 19. | FMS - Automated Extraction and Cleanup of Toxaphene in Soils, Sediment and Fish
Toxaphene does not occur naturally in the environment. It is widely found in the environment, mainly
as a result of past releases to air, water,... |
|
| 20. | Automated One Step SPE and Concentration of Nitrogen and Phosphorus Containing Pesticides in Water
Replacing organochlorine pesticides, nitrogen and phosphorus containing pesticides are widely used
both domestically and globally. Initially... |
|
| 21. | Improved Extraction and LC-MS-MS Analysis of Barbiturates from Urine Samples Using
Strata™-X-Drug N SPE and Kinetex® Core-Shell HPLC/UHPLC Columns
Utilizing a fast and simplified solid phase extraction (SPE) procedure with Strata-X-Drug N,
barbiturates from urine samples were concentrated... |
|
| 22. | Antibiotics in Beef or Serum Using QuEChERS
A streamlined QuEChERS sample preparation method is described for several classes of antibiotics in
beef, kidney juice, or serum. Antibiotics... |
|
| 23. | A Novel Sample Preparation Device for Improved Phospholipid Removal in Bioanalytical Assays
Matrix effects are residual components of biological matrix that alter mass spectrometry response,
decrease method robustness, add to method... |
|
| 24. | Cyromazine Analysis in Poultry Feed Using a QuEChERS Approach
A procedure is described for the analysis of the insecticide additive cyromazine (Trigard or Larvadex)
in poultry feed by LC-MS-MS. Extract... |
|
| 25. | One Step Extraction, Cleanup and Concentration of PCBs in Soil
Due to PCBs toxicity and classification as a persistent organic pollutant, PCB production was banned
by the United States Congress in 1979 and by... |
|
| 26. | Rapid Metabolite Identification using MetabolitePilotTM Software
This technical note describes how MetabolitePilotTM software and the AB SCIEX TripleTOFTM5600 System
can make the process of identifying and... |
|
| 27. | Tracking Flavours in White Wine and Coffee Flavour Profiling of Food Samples with SPME-GC–MS
and On-column Injection
SPME-GC–MS with on-column injection can be successfully employed for flavour profiling
of food samples. The on-column injector of the... |
|
| 28. | On-line SPE-LC of Catecholamines in Urine with Fluorescence Detection
Catecholamines are important markers for the diagnosis and management of tumour diseases of the
sympathoadrenal system. The major catecholamines... |
|
| 29. | High Throughput Extraction of Melamine using EVOLUTE CX Mixed-mode SPE Plates
The use of EVOLUTE CX mixed-mode columns provides high and consistent recoveries across a range of
complex matrices, from biological fluids to... |
|
| 30. | Headspace Analysis of Volatile Organic Compounds (VOCs) in Contact Packaging Materials Using the HT3
Automated Headspace Analyzer
The United States Food and Drug Administration (U.S. FDA) and the European Union (EU) have published
regulations and provided guidance on the use... |
|
| 31. | Automated Handling Techniques for the Analysis of Elevated Volatile Organic Compound (VOC) Concentrations in
Soils Utilizing the Atomx Concentrator/Multimatrix Autosampler
In U.S. EPA Method 5035 there are two collection options for samples containing high levels of
volatile organic compounds (VOCs). The first... |
|
| 32. | Total Rapid Prep for Same Day Turnaround of POPs Analysis
Human health not only depends on providing good medical care, but also on the priority given to
prevent exposure to environmental and other... |
|
| 33. | Two Novel Polysaccharide-Based Chiral Stationary Phases: CHIRALPAKˆ® AY-H and
CHIRALCELˆ® OZ-H
Polysaccharide-based chiral stationary phases (CSP) are successfully employed to achieve the majority
of analytical and preparative... |
|
| 34. | A Novel Approach for Sample Adsorption and Extraction Using A Monolithic Hybrid Adsorbent As A New
Generation Medium
Conventional media for sample adsorption and extraction, stir bar sorptive extraction (SBSE) and
solid-phase microextraction (SPME) are used in... |
|
| 35. | The Integration of Microextraction Packed Sorbent (MEPS) into Multidimensional Strategies
LC/GC approaches to analysis are attractive because they combine the selectivity of solid-phase
sorbents in the first dimension with the... |
|
| 36. | Trace Level Analysis of Melamine in Milk Products on 7890A/5975C Using a New Agilent J&W DB-5ms
Ultra Inert Column and SamliQ SCX Cartridges
GC–MS method is presented for the quantitative determination and confirmation of
melamine residues in milk products. The milk sample was... |
|
| 37. | Extraction of Corticosteroids from Plasma using ISOLUTE SLE+ Supported Liquid Extraction Plates
This application note from Biotage describes the extraction of 15 corticosteroids from human plasma
using ISOLUTE SLE+ Supported Liquid... |
|
| 38. | US EPA Method 8260 Performance Evaluation with the Stratum PTC and SOLATek 72 Multi-Matrix
Autosampler
EPA Method 8260 is used to determine volatile organic compounds (VOC's) in a variety of matrices
including ground and surface waters. This method... |
|
| 39. | Reversed-Phase Enantioselective Chromatography with New µ-mm Chiral Stationary Phases
To meet the growing need for fast reversed-phase enantiomer separations, two new
3-μm reversed-phase columns,... |
|
| 40. | Memory Effects of Mobile Phase Additives on the Whelk-O®1 Chiral Phase
The Pirkle - Type Whelk-O®1 CSP is a synthetically made chiral selector
covalently bonded to a silica support. This phase is well... |
|
| 41. | The Integration of Microextraction Packed Sorbent (MEPS) into Multidimensional Stratagies
LC–GC approaches to analysis are particularly attractive because they combine the
selectivity of solid phase sorbents in the first... |
|
| 42. | Residual Solvents by HT3™ Headspace in Reference to USP <467> with a
Comparison of Static Versus Dynamic Headspace Analysis
Residual solvents in pharmaceuticals are defined as volatile organic chemicals that are used or
produced in the manufacture of drug substances,... |
|
| 43. | Removal of Endogenous Matrix Components Using EVOLUTE® CX Mixed-Mode Cation Exchange Solid Phase
Extraction
Sample preparation is an essential technique to remove unwanted matrix components prior to
LC–MS-MS analysis of drugs in biological fluids.... |
|
| 44. | EVOLUTE CX, an Advanced SPE Solution for the Removal of Proteins and Phosphoplipids from Plasma
This application note from Biotage describes the effective removal of two major classes of matrix
components, proteins and phospholipids, using... |
|
| 45. | A Highly Sensitive Method for the Analysis of Tamsulosin (Flomax) in Human Plasma
A highly sensitive analytical method for the analysis of tamsulosin in human plasma has been developed
for use in bioanalytical studies. The... |
|
| 46. | On-line SPE-LC of Catecholamines in Urine with Fluorescence Detection
Catecholamines are important markers for the diagnosis and management of tumour diseases of the
sympathoadrenal system. The major catecholamines... |
|
| 47. | The Analysis of Small Brominated and Chlorinated Aromatic Compounds using MEPS
The wine industry has long been a sufferer of TCA (2,4,6-trichloroanisole) and TBA
(2,4,6-tribromoanisole) contamination or "cork" taint.... |
|
| 48. | On-line Sample Pretreatment of Biological Samples Using Shim-pack MAYI Columns
Dedicated therapy with low concentrated pharmaceuticals requires drug monitoring to avoid overdoses
and maintain the effective concentration.... |
|
| 49. | Isolation and Purification of Polysaccharides
In the last few decades, the novel functions of polysaccharides have provided a major impetus for
increasing scientific attention. Among the most... |
|
| 50. | Multi-Residue Analysis of Pesticides in Fruits Using DisQuE, a Dispersive Solid-Phase Extraction Kit
A new technique, QuEChERS, standing for Quick, Easy, Cheap, Effective, Rugged, and Safe, is readily
accepted by both the AOAC International and... |
|
| 51. | Polar-Modified Stationary Phases: An Ideal Choice for the Analysis of Nucleotides
Out of the several options available for retaining polar compounds like nucleotides, this application
note focuses on the use of polar-modified... |
|
| 52. | Investigation of Branched Polydienes with GPC/MALS
Our work focuses on the synthesis of branched (functionalized) polydienes via a facile two-step
synthesis. Despite the numerous strategies... |
|
| 53. | Techniques for Reducing Purge-and-Trap Cycle Times in VOC Analysis
The purge-and-trap (P&T) technique for analysis of volatile organic compounds (VOCs) was
pioneered in the 1970s at the United States... |
|
| 54. | Automated SEC of Low Molecular Mass Heparins According to Pharmaeuropa
Low molecular mass heparins are salts of sulphated glucosaminoglycans having a mass average molecular
mass less than 8000. At least 60% of the... |
|
| 55. | Removal of Endogenous Matrix Components Using EVOLUTE&® CX Mixed-Mode Cation
Exchange Solid Phase Extraction
Sample preparation is an essential technique to remove unwanted matrix components prior to
LC–MS-MS analysis of drugs in biological fluids.... |
|
| 56. | Effect of Varying Co-Solvents in SFC Method Development on a Whelk-O 1® Chiral Stationary
Phase
Supercritical Fluid Chromatography (SFC) is quickly becoming a popular choice by chromatographers for
analytical and preparative separations. |
|
| 57. | On-Site Sample Preparation Using MEPS for Waste Water Analysis
MEPS uses a barrel insert and needle (BIN) device to reduce Solid-Phase Extraction (SPE) to a
micro-scale suitable for small volume samples and... |
|
| 58. | Extraction of Basic Drugs from Plasma Using EVOLUTE CX 96-well Plates and Columns
The use of mixed-mode solid-phase extraction (SPE) provides significant selectivity advantages
compared with non-polar resin-based SPE.... |
|
| 59. | A Highly Selective Method for the Analysis of Drospirenone in Human Plasma
Several common birth control formulations contain both drospirenone and ethinyl estradiol. A highly
selective and sensitive analytical method for... |
|
| 60. | Evaluation of Extraction Methods and Bias Correction by EPA Method 6800 Protocol for Mercury Species in Tuna
Fish Tissue Using an Ion Chromatograph Coupled to an ICP–MS
Mercury pollution mainly originates from industrial activities such as chlorine production, rubbish
incineration and above all coal-fuelled power... |
|
| 61. | Isolation and Purification of Polysaccharides
In the last few decades, the novel functions of polysaccharides have provided a major impetus for
increasing scientific attention. Among the most... |
|
| 62. | Automated Extraction Technique for Improved Recovery of Phenols
Dionex has developed a new standard for flow-through solvent extraction which allows accelerated
solvent extraction (ASE) of matrices that have... |
|
| 63. | Automated Sample Clean-Up of Olive Oil
Gel permeation chromatography (GPC) has been used as an effective clean-up procedure for removing high
molecular weight interfering molecules... |
|
| 64. | Meeting the Updated Requirements for the Determination of Residual Solvents in Pharmaceutical
Materials
The United States Pharmacopeia (USP) has implemented a revised method for the determination of
residual solvents, chapter 467; this revision has... |
|
| 65. | Quick and Easy Membrane Characterization with GPC-SEC
Size exclusion chromatography is a powerful tool for the characterization of molecules differing in
size and molar mass. It is widely used and... |
|
| 66. | Comparing Selectivity of Phenylhexyl and Other Types of Phenyl Bonded Phases
A new phenylhexyl bonded phase provides an alternative selectivity for optimizing HPLC method. This
also applies when different types of phenyl... |
|
| 67. | Effect of Varying Co-Solvents in SFC Method Development on a Whelk-O 1® Chiral
Stationary Phase
Supercritical Fluid Chromatography (SFC) is quickly becoming a popular choice by chromatographers for
analytical and preparative separations. |
|
| 68. | On-site Sample Preparation Using MEPS for Waste Water Analysis
MEPS uses a barrel insert and needle (BIN) device to reduce Solid-Phase Extraction (SPE) to a
micro-scale suitable for small volume samples and... |
|
| 69. | Extraction of Basic Drugs from Plasma Using EVOLUTE CX 96-Well Plates and Columns
his application note describes the extraction of a variety of basic drugs from plasma using EVOLUTE CX
mixed-mode resin-based SPE. The analyte... |
|
| 70. | Application of Automated SPE of Chlorinated Pesticides and PCBs in Wastewater Using Certified for Automation
Atlantic C18 SPE Disks
As a result of the persistent nature of chlorinated compounds in the environment there is still a
critical need for monitoring these compounds.... |
|
| 71. | On-Line Sample Clean-Up for the LC–MS Analysis of Small Molecules in Serum
Drug discovery/detection commonly focuses on analytes which are present in biological matrices. Direct
injection of such samples onto LC and... |
|
| 72. | Determination of Geosmin and 2-MIB in Drinking Water by SPME-PTV-GC–MS
This application describes the analysis of two key taste and odour compounds in drinking water using
solid-phase microextraction and gas... |
|
| 73. | Extraction of Basic Drugs from Plasma Using EVOLUTE CX 96-well Plates and Columns
|
|
| 74. | EPA Method 608: Application of Automated SPE of Chlorinated Pesticides and PCBs in Wastewater Using
Certified for Automation Atlantic C18 SPE Disks
|
|
| 75. | A Screening Process for Development of Enantioselective Supercritical Fluid Chromatography Separation
Methods
|
|
| 76. | GPC of Polythiophene
|
|
| 77. | Generic Procedure for the Extraction of Diuretics from Urine Using EVOLUTE ABN SPE Columns
|
|
| 78. | Tips to Meeting the Criteria of the Upcoming Revised USP Monograph <467>: Residual
Solvents
|
|
| 79. | Alternate Selectivity for Bases in UltraPerformance Liquid Chromatography Using a Non-Endcapped High
Strength Silica Stationary Phase
|
|
| 80. | Effect of Varying Co-Solvents in SFC Method Development on a Whelk-O 1 Chiral Stationary Phase
|
|
| 81. | Accurate, Reliable Fractionation of Extractable Petroleum Hydrocarbons
|
|
| 82. | Techniques for Reducing Purge-and-Trap Cycle Times in VOC Analysis
|
|
| 83. | Comparison of Titanium Dioxide & Zirconium Dioxide SPE Tips for Phosphopeptide
Enrichment
ZirChrom Separations, Inc. |
|
| 84. | Application of Automated Solid Phase Extraction for Determination of Polychlorinated Biphenyls (PCB) in
Water
Horizon Technology, Inc. |
|
| 85. | On-Line and Off-Line Application of Micro-SPE (MEPS)
Peter Dawes, Ern Dawes, and Paul Wynne, SGE Analytical Science |
|
| 86. | Accelerated Solvent Extraction: Sample Preparation for Determination of Brominated Flame Retardants
Peterson, J. H., Carlson, R. E., Murphy, B.J., and Richter, B. E., Dionex Corporation |
|
| 87. | Accelerated Solvent Extraction: Sample Preparation for Determination of Brominated Flame Retardants
|
|
| 88. | Improving Sample Introduction in Arson Investigation Through Sample Re-Collection in Automated Thermal
Desorption
The process of investigating a suspicious fire includes many different types of analyses. An essential
step in confirming the presence of a... |
|
| 89. | Increased Sample Throughput with Luna? HILIC - Phenomenex
Increased Sample Throughput with Luna? HILIC |
|
| 90. | Increased Sample Throughput with Luna® HILIC — Phenomenex
Increased Sample Throughput with Luna® HILIC |
|
| 91. | The Isolation of Three β-blockers from Human Plasma using ISOLUTE SLE+ Supported Liquid
Extraction 96-well Plates
Simple, efficient sample preparation techniques are essential to the success of high throughput
bioanalytical assays. Techniques such as protein... |
|
| 92. | On-Line and Off-Line Application of Micro-SPE (MEPS)
Solid-phase extraction (SPE) has revolutionized sample preparation. Variations on the technique offer
enhanced recovery, greater speciation and... |
|
| 93. | Automated Sample Re-collection for Thermal Desorption Sampling
The TurboMatrix 650 ATD incorporates technology, allowing a portion of desorbed sample vapour, which
would otherwise be lost through sample... |
|
| 94. | SPE Sample Preparation for UPLC–MS Determination of Enrofloxacin (Baytril) in Chicken
In 2005, FDA banned the use of the enrofloxacin (Baytril) for growth enhancement in poultry
production. Prior to this ruling, an LOQ of 10... |
|
| 95. | Deglycosylation and Sample Clean-up Method for Mass Spectometry Analysis of N-linked Glycans
A rapid method for the analysis of glycans is presented. This method describes deglycosylation of
glycoproteins aided by an enzyme-friendly... |
|
| 96. | MISP (Metrohm Inline Sample Preparation) — Direct Analysis of Anions in Gasoline after Matrix
Elimination
Metrohm Inline Sample Preparation (MISP) is a proven technique for automating sample preparation steps
in Ion Chromatography that until now, had... |
|
| 97. | Micro Scale Solid-Phase Extraction: Decrease Your Sample Size by 50% while Increasing Sensitivity by 10X
without Matrix Suppression
The ?Elution technology combines a patented plate design, proven Oasis®
chemistries... |
|
| 98. | Dialysis ? A Unique Proven Sample Preparation Technique for Ion Chromatography
What is dialysis? Dialysis is a membrane-based sample preparation technique, which has recently been
employed by Metrohm for . . . |
|
| 99. | Simplified Method Development for the Extraction of Acidic, Basic and Neutral Compounds
SPE has become a popular sample preparation technique that bridges the gap between specimen,
collection and instrumental analysis... |
|
| 100. | Fast and Easy Physiological Amino Acids Analysis in 15 Minutes
Due to the complex chemical composition of urine and serum samples, the analysis of physiological
amino acids has often been difficult... |
|
