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Gas chromatography-mass spectrometry (GC-MS) is a hyphenated technique which combines the separating power of gas chromatography (GC) with the detection power of mass spectrometry (MS). Mass Spectrometry is a wide-ranging analytical technique, which involves the production and subsequent separation and identification of charged species according to their mass-to-charge (m/z) ratio. GC-MS covers a broad range of application areas. This module will explore the instrument acquisition methods used and examine the type of data that can be produced from such systems.

 

Topics include:

  • Definitions
  • GC instrument fundamentals
  • MS instrument fundamentals
  • GC-MS process
  • Why and when to use GC-MS
  • Coupling GC to MS systems
  • Ionization overview