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CHROMtalks - GC Column Selection: The Three Most Important Parameters to Consider

In gas chromatography (GC), separation relies of analyte volatility and polarity. The choice of GC column is paramount to achieve good resolution in an efficient timeframe. In this talk, I will first give an overview of the separation mechanism in GC. Then I will discuss several important parameters to consider when selecting a capillary GC column. I will spend the bulk of the time describing column chemistry, which is the most important consideration when establishing a new GC method. Finally, I will show examples from my own research showing the importance of column selection.

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