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Principles
Technique
Instrumentation
Troubleshooting
Method Development
Miscellaneous
Learning Paths

Technique
Learning Paths

Principles
Technique
Instrumentation
Troubleshooting
Method Development
Learning Paths

Principles
Technique
Instrumentation
Troubleshooting
Method Development
Learning Paths

Principles
Technique
Learning Paths

Technique
Troubleshooting
Learning Paths

Principles
Technique
Instrumentation
Miscellaneous
Learning Paths

Modules

Method Validation - Principles
Mobile Phase Considerations
HPLC Band Broadening
HPLC Introduction
Column Chemistry
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Quick Guides

HPLC Mobile Phase Lifetimes
Buffer Choice for HPLC Separations
HPLC Filtration - Rocks, Boulders, and Sand
I Only Ever Need C18 for Reversed Phase Chromatography Don’t I?
HPLC Extra Column Volumes
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Webcasts

The Rights and Wrongs of Mobile Phase Preparation Q&A
The Rights and Wrongs of Mobile Phase Preparation
Top 10 Tips for Selecting HPLC Column Chemistry and Dimensions
20 Steps to a Reliable HPLC Mobile Phase
What HPLC Operators Need to Know Part 2: Column Selection, Mobile Phase Gradients, and Detectors
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Video Courses

Fundamentals of HPLC Video Training Course

Modules

Method Validation - Technique
Mixed-Mode HPLC
Quantitation and Calibration
Ion Chromatography
Supercritical Fluid Chromatography
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Quick Guides

HPLC Derivatization
HILIC Mechanism and Stationary Phase
HILIC Conditioning and Equilibration
How to Choose a Stationary Phase for HILIC
Ion Pair Alternatives
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Webcasts

Statistics 101
CHROMTalks HPLC Series
Hydrophilic Interaction Chromatography (HILIC) and Related Techniques
Making HILIC Work for You
Understanding Gradient HPLC
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Modules

HPLC Detectors
HPLC Solvent Pumping Systems
Autosamplers

Quick Guides

Batch Integration
HPLC Essentials - Switching Between Reversed and Normal Phase
HPLC Essentials - System Dwell Volume
Essential HPLC Protocols
5 Diode Array Detector Settings That Should be Optimized
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Webcasts

Everything You Need to Know About UV Detectors for HPLC
Top 10 Features of a Successful Chromatography Data System - Part 1
HPLC Detectors – What, Where, When, and How
Top 10 Features of a Successful Chromatography Data System - Part 2
Everything You Should Know About UV Detection for HPLC
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Modules

Troubleshooting Extra Peaks in HPLC

Quick Guides

HPLC Troubleshooting Strategy
HPLC Troubleshooting Guide to Peak Fronting and Poor Sensitivity
HPLC Troubleshooting – Retention Time and Baseline Issues
HPLC Troubleshooting - More Split Peaks
HPLC Troubleshooting Video - Peak Tailing
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Webcasts

HPLC Extra Peaks and Contamination
Mobile Phase Issues
HPLC Column Issues
HPLC Method Reliability
HPLC Method Troubleshooting
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Modules

Fast HPLC

Quick Guides

Speeding Up Your HPLC
You Need a Fancy System to Run Fast HPLC – Or Do You?
Three Quick Tips to Improve HPLC Method Development
How U is Your UHPLC?
Is the Art of HPLC Method Development Dead?
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Webcasts

Developing Better Methods for Reversed Phase HPLC
Chromatographic Method Validation
Translating and Transferring HPLC Methods
Developing Better HPLC (MS) Methods

Video Courses

HPLC Method Development Video Training Course

Modules

HPLC Interactive Tools

Modules

GC Columns
GC Introduction
GC Chromatographic Parameters
GC Band Broadening

Quick Guides

Packed or PLOT GC Columns for Gas Analysis?
GC Band Broadening - Longitudinal Diffusion
GC Chromatographic Parameters - Efficiency
GC Columns - Analyte/Stationary Phase Interactions
How Important is it to Know the Correct GC Column Length?
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Webcasts

Choosing the Right GC Column - The Most Important Choice You Will Ever Make
How to Select the Optimum GC Column
Column Selection for Capillary GC

Video Courses

Fundamentals of GC Video Training Course

Modules

Practical GC Video Bootcamp
GC Sampling Techniques
GC Temperature Programming

Quick Guides

GC Derivatization
GC Sampling Techniques - Headspace
The Why, What, and How of Headspace GC
Optimizing GC Temperature Programming

Webcasts

CHROMTalks GC Series
GC Temperature Programming - 10 Things You Absolutely Need to Know
Everything You Should Know About Headspace GC
Tips and Tricks for Successful GC Temperature Programming

Modules

GC Sample Introduction
GC Detectors
Gas Supply and Pressure Control

Quick Guides

GC Autosampler Setup
Best Practice for GC Sample Introduction
5 Ways to Improve Your Split/Splitless Injection Technique
How to Optimize Key Variables in GC Analysis - Sample Introduction
Do We Need Glass Wool in a GC Inlet Liner?
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Webcasts

Preventative GC Maintenance
Optimizing GC Detectors
What GC Operators Need to Know: Part 1
What GC Operators Need to Know: Part 2
Crimes Against Laboratory Gases
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Quick Guides

Practical GC Troubleshooting - Reduced Sensitivity
10 Common GC Mistakes
GC Troubleshooting Guide to Broad Peaks and Loss of MS Sensitivity
Practical GC Troubleshooting Video - Peak Tailing
Practical GC Troubleshooting Video - Peak Splitting
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Webcasts

GC Troubleshooting - Gas Supply and Inlet Issues
GC Troubleshooting in 20 Pictures - Part I
GC Troubleshooting in 20 Pictures - Part 2
GC Troubleshooting - Column and Detector Problems
Troubleshooting GC Separation Part II – Selectivity, Resolution, and Baseline Issues
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Webcasts

Automated Derivatization for Gas Chromatography
A More Cost-Effective Carrier Gas for Volatile Organic Compound Analysis
Air Monitoring: What are the Right Tools for the Job?
Understanding 2D Gas Chromatography
Developing Fast Capillary GC Separations
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Video Courses

GC Method Development Video Training Course

Modules

GC Interactive Tools

Modules

QuEChERS
SPE Method Development
SPE Overview
Molecular Properties
Primary Sample Preparation Techniques
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Quick Guides

Soxhlet Extraction
Vacuum or Positive Pressure: Which is Best for SPE Processing?
Sample Preparation - Microextraction: SDME
SPE - Troubleshooting Recovery Problems
SPE - Column Conditioning
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Webcasts

CHROMTalks Sample Preparation Series
Everything You Need to Know About Filtration
Troubleshooting Sample Preparation: Filtration, LLE, SLE, and SPE
Crimes Against Laboratory Gases
Improved Speed of Extractables Studies Using Accelerated Solvent Extraction and LC-MS
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Modules

GC-MS Introduction

Webcasts

Understanding GC-MS Analysis

Video Courses

Fundamentals of GC-MS Video Training Course

Modules

Practical GC-MS Video Bootcamp
GC Considerations
GC-MS Ionization

Quick Guides

GC-MS Column Selection
GC-MS Ionization Quick Guide
Fundamentals of GC-MS Ionization Techniques

Webcasts

Understanding Electron Ionization for GC-MS
GC-MS Ionization Processes
What GC-MS Operators Need to Know
GC-MS/MS Analysis – What You Need to Know!

Modules

GC-MS Vacuum Systems
GC-MS Sample Introduction
Introduction to Mass Analyzers
Quadrupole Mass Analyzers
Time-of-Flight (ToF) Mass Analyzers
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Quick Guides

GC-MS Solvent Delay
Vacuum Pump Maintenance
What Can a GC-MS Tune Report Tell You?

Webcasts

Crimes Against Laboratory Gases

Quick Guides

GC-MS Contamination
GC-MS Leak Detection

Quick Guides

Do You Know What is in Your Beer?
Does Mass Spectrometry Need Chromatography?
Improving Sensitivity of Environmental GC-MS Analysis

Webcasts

Translating GC and GC-MS Methods
The Secrets of Optimizing GC-MS Methods
Optimizing GC-MS and GC-MS/MS Analysis for Environmental Applications

Modules

Free LC-MS Video Training
Electrospray Ionization (ESI) Theory
Atmospheric Pressure Chemical Ionization (APCI) Theory
Atmospheric Pressure Photoionization (APPI) Theory
LC-MS Introduction
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Video Courses

Fundamentals of LC-MS Video Training Course

Modules

Practical LC-MS Video Bootcamp
LC-MS Interpretation
Atmospheric Pressure Chemical Ionization (APCI) Technique
Atmospheric Pressure Photoionization (APPI) Technique
Electrospray Ionization (ESI) Technique
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Quick Guides

LC-MS - Effect of Solvent Type and pH
10 Must Know Points to Understand Electrospray Ionization
New to LC-MS? 10 Practical Tips That Will Make a Real Difference
7 Must Know Points to Understand Atmospheric Pressure Chemical Ionization

Webcasts

CHROMTalks Mass Spectrometry Series
What LC-MS Operators Need to Know
Optimizing API Interfaces
LC-MS Method Parameters - Critical Evaluation
Electrospray Ionization (ESI) for LC-MS
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Modules

Time-of-Flight (ToF) Mass Analyzers
Electrospray Ionization Instrumentation
Introduction to Mass Analyzers
Vacuum Systems
Orbitrap Mass Analyzers
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Quick Guides

Vacuum Pump Maintenance
Everything You Need to Know About LC-MS Tuning and Calibration

Webcasts

Fundamentals of Triple Quadrupole MS in Applied Markets
Understanding Mass Analyzers - Traps and ToFs
Quadrupole Analyzers and MS/MS Analysis

Quick Guides

ESI Signal Suppression
10 Ways to Break Your LC-MS
Controlling Na and K Adducts in LC-MS
10(ish) Ways to Prevent LC-MS Contamination
Avoiding LC-MS Signal Suppression
+ VIEW MORE GUIDES

Webcasts

Troubleshooting LC-MS

Modules

Electrospray Ionization eLab
Atmospheric Pressure Chemical Ionization eLab
Atmospheric Pressure Photoionization eLab
Flow Rates and Flow Splitting eLab
Solvents, Buffers, and Additives eLab
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Quick Guides

LC-MS - Introduction to MS/MS Experiments
Does Mass Spectrometry Need Chromatography?
10 Tips For Great LC-ESI-MS Results
Quick LC-MS Method Optimization

Webcasts

Optimizing LC-MS and LC-MS/MS

Modules

Introduction to IR Spectroscopy

Webcasts

Introduction to Infrared Spectroscopy
Fundamentals of ICP-MS
Fundamentals of ICP-OES
Fundamentals of Atomic Absorption Spectroscopy

Modules

Infrared Spectral Interpretation
UV-Visible Spectroscopy

Modules

Automatic Pipettes
Balances
Errors
Laboratory Safety
Volumetric Lab Equipment
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Quick Guides

10 Questions We've Been Asked About Balances

Webcasts

Tips and Tricks to Improve Essential Lab Practices: Weighing, Pipetting, and Volumetric Glassware
Coping With COVID-19: Remaining Productive and Safe in the Analytical Laboratory

Quick Guides

Top 10 Pipetting Mistakes

Modules

Biopharmaceuticals
Fundamentals of MS Proteomics Research
Introduction to Mass Spectrometry for Biomolecules
Introduction to Biopharmaceutical Analysis
mAbs - Introduction to Monoclonal Antibodies
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Quick Guides

Fundamentals of Biomolecules
The Fundamentals of HPLC Peptide Analysis
The Fundamentals of Glycan Analysis
Introduction to Amino Acid Analysis in Biopharmaceuticals

Webcasts

Native and Denaturing Mode Size Exclusion Analysis of Biotherapeutics
N-Glycan Sample Prep and Analysis Workflows for Screening and Characterization of Biotherapeutics
Purification and Analysis of Synthetic Peptides: The Challenges of Method Development
The Power of LC-MS in the Characterization of Protein Biopharmaceuticals
The Analysis of Post-Translational Modifications Using LC-MS/MS
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Modules

Introduction to Ion Mobility Spectrometry (IMS)
Mass Spectrometry at the Glycan Level
Mass Spectrometry at the Peptide Level
Reversed Phase - Protein Level Analysis and Optimization
HILIC for Biomolecules
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Quick Guides

Demystifying Reversed Phase Column Selection for Biomolecule Analysis
First Steps in Characterizing Biotherapeutics
Reversed Phase HPLC for the Analysis of Biomolecules
HILIC, IEX, and SEC for the Analysis of Biomolecules
Selecting Columns and Initial Conditions for IEX and SEC Biomolecule Analysis
+ VIEW MORE GUIDES

Webcasts

In-depth Characterization of Biopharmaceuticals by Multidimensional LC-MS
Tips to Optimize Lab Scale Oligonucleotide Purification
High-throughput and High-resolution N-glycan Profiling Workflows Using InstantPC
Introduction to Peptide Analysis by HPLC
Identification, Mapping, and Relative Quantitation of SARS-CoV-2 Spike Glycopeptides by Mass-Retention
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