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This webinar discusses the two main forms of ionization, electron ionization (EI) and chemical ionization (CI) in GC-MS. The molecular reactions which occur within the ion source to produce ions will be examined along with which form of ionization should be used for particular analytes. Finally, our speakers will impart some of their expert knowledge regarding optimization of the GC-MS process and some general interpretation strategies. 


Topics include:

  • Why use GC-MS
  • Anatomy of a typical ion source
  • Electron and chemical ionization – explanation of key parameters and how they effect your analysis
  • How to improve sensitivity and specificity by manually tuning source parameters
  • Recognizing ionization problems in your chromatographic and mass spectral data
  • Analyte fragmentation and basic interpretation strategies