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The CHROMacademy Essential Guide Webcast:
What GC-MS Operators Need to Know

Wednesday 5th September 2018,
8:00am PDT/ 11:00am EDT/ 4:00pm BST/ 5:00pm CEST



This informative webcast will discuss special GC considerations, how analyte ionization works, and the principles of mass analysis using quadrupole devices.  We will show you how to interpret an MS tune report, the power of various MS operating modes, and how to process and understand the data you generate.  This essential information will allow you to better implement this technique successfully in your laboratory.

Presented by
Dr. Dawn Watson (CHROMacademy Technical Expert, Crawford Scientific)

Topics Covered

  • Essential sample preparation troubleshooting strategies
  • Why do we use MS detectors with GC?
  • Vacuum – don’t be scared!
  • What special GC considerations are there when working with MS detectors
  • Setting GC acquisition parameters
  • Electron ionization (EI) and chemical ionization (CI)
  • Quadrupole mass analyzers
  • Understanding tune reports
  • Setting MS acquisition parameters
  • Understanding GC-MS data

Presenter Information »


What GC-MS Operators Need to Know

This month’s webcast focused on the practical aspects of GC-MS.  This included GC considerations, such as, column dimensions and column stationary phase type and the impact these parameters can have on the physical operation of the instrument and the results obtained. We also discussed the theory of GC-MS in relation to ionization, types of MS experiment, and how to analyze data.  This webcast is essential viewing for al GC-MS users.

Our Quick guides, CHROMacademy course content, and archived webcasts and tutorials will provide you with further knowledge on how to implement, optimize, and troubleshoot GC-MS applications.

Watch the webcast
eLearning Modules

Fundamental GC-MS: Introduction

This module introduces the technique of GC-MS.  The topics covered will provide information on the types of analytes which can be analyzed, how the GC-MS process works, the basic principles of analyte ionization, as well as information on the different types of mass analyzer which are used.

GC-MS Process | Coupling GC to MS systems
Ionisation Overview | Mass Analysers - Overview


Fundamental GC-MS: GC Considerations

This module provides information on the aspects of the GC separation and instrument setup which must be considered in relation to GC-MS analyses.

Sample Introduction | Columns
Stationary Phases | GC-MS Column Selection


Quick Guides

GC-MS Contamination

Contamination is an insidious problem in GC-MS.  This quick guide will help you to identify and avoid common sources of GC-MS contamination, which in turn will provide you with more reliable results, less system maintenance, and fewer instances of troubleshooting.

GC-MS Contamination »


Improving Sensitivity of Environmental GC-MS Analysis

As with many sectors, detection limits for analytes in environmental samples are becoming ever lower. This challenges every step of the analytical process from sampling, to sample preparation, and the use and implementation of instrumentation which can provide the best sensitivity. Every step must be optimized to meet these sensitivity criteria, and, in this article, we will look at some areas of the GC-MS method which can be optimized to provide the optimum sensitivity.

Improving Sensitivity of Environmental GC-MS Analysis »


Do You Know What’s in Your Beer?

Citrus, grapefruit, toffee, spice, apple, pear, biscuit, caramel… the list of flavors and aromas associated with beer is vast but how are they produced during the brewing process?  The hop variety used in the brewing process is responsible for the bitterness, aroma, and flavor characteristics.  These compounds can be extracted from hops by steam distillation, liquid-liquid extraction and analyzed using GC-MS.

Do You Know What’s in Your Beer? »


Fundamentals of GC-MS Ionization Techniques

Understanding how an instrument works is great, but when do you have time to read a text book, or go to a course? Let CHROMacademy help. Dip in and out of concise modules and take 5 minutes to learn a little about the fundamentals of your analytical technique. Why not delve into GC-MS ionization techniques right now?

Fundamentals of GC-MS Ionization Techniques »


GC-MS Leak Detection

A practical guide for identifying and fixing leaks in GC-MS instruments.

GC-MS Leak Detection »


GC-MS Ionization Processes

The focus of this Essential Guide webcast is GC-MS ionization processes.  The two main forms of ionization, electron ionization (EI) and chemical ionization (CI), will be discussed in depth.  The molecular reactions which occur within the ion source to produce ions will be examined along with which form of ionization should be used for particular analytes.  We will also impart some of our expert knowledge regarding optimization of the GC-MS process and some general interpretation strategies.

GC-MS Ionization Processes »


GC-MS/MS Analysis: What You Need to Know

In this session, we explore the theory, technology, and applications of GC-MS/MS. We will discuss the key features of GC-MS/MS instrumentation alongside an overview of the key instrument operating principles and theories. Various means of deriving MS/MS spectral information will be discussed with reference to the analyzers which make these experiments possible and key applications of MS/MS technology will be highlighted to demonstrate practical relevance and show what GC-MS/MS technology can do for you!

GC-MS/MS Analysis: What You Need to Know »


The Secrets of Optimizing GC-MS Methods

The definitive guide to optimizing methods for GCMS analysis.  In this session we consider the major instrument and method decisions that allow you to get the very best from your analysis. 

The Secrets of Optimizing GC-MS Methods »

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Dr. Dawn Watson CHROMacademy Technical Expert
Crawford Scientific

Dawn completed her PhD in synthetic inorganic chemistry at the University of Strathclyde, Glasgow, followed by postdoctoral research on small molecule reaction kinetics at Princeton University.

Following several years working for a major instrument manufacturer, she became a technical expert for CHROMacademy in 2013.

She has expertise in various analytical techniques, including HPLC, GC, GC–MS, LC–MS, NMR, and molecular spectroscopy.  As well as numerous wet chemistry and sample preparation techniques.