The Power of LC-MS in the Characterization of Protein Biopharmaceuticals

Protein biopharmaceuticals such as monoclonal antibodies and recombinant proteins are currently in widespread use for treatment of various life-threatening diseases including cancer, autoimmune diseases, diabetes, anemia, etc. Protein therapeutics have a complexity far exceeding that of small molecule drugs, hence, unraveling this complexity represents an analytical challenge.

This webcast will highlight the power of liquid chromatography combined with mass spectrometry in the characterization of protein biopharmaceuticals.

Topics include:

• Introduction to protein biopharmaceuticals
• Analytical tools for protein characterization
• Case study: biosimilar/biobetter development