Translating GC and GC-MS Methods

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The definitive guide for translating GC and GC-MS methods. We explore the various reasons for translating methods including improved chromatography, faster throughput, adopting modern column geometries, and switching to hydrogen carrier from helium. All aspects of instrument hardware and method variable translation will be detailed and you will leave with a toolkit approach for translating your own methods which will save you time, money, and improve your chromatography!

 

Topics include:

  • Key reasons and benefits of translating GC and GC-MS methods
  • Translating for speed, efficiency, or to hydrogen from helium
  • Maintaining retention time
  • Avoiding selectivity changes in temperature programmed GC
  • Effects of changing carrier on detector performance and sensitivity
  • MS detector considerations
Translating GC and GC-MS Methods