CHROMtalks - Micro- and Nanoplastic Quantification Using Pyrolysis GC-MS: The Hidden Complexity

To accurately assess the extent and impact of micro- and nanoplastic pollution in the environment, as well as their potential toxicity, robust analytical techniques are essential. Among existing methods, pyrolysis–gas chromatography–mass spectrometry (Py-GC–MS) has emerged as a promising tool for the identification and quantification of micro- and nanoplastics. However, behind the apparent simplicity of this technique lies a hidden complexity. A thorough understanding and careful optimization of the pyrolysis process are required for reliable GC–MS analysis. Critical factors - such as matrix effects, particle size, and selection of quantifier ions - are often overlooked, despite their substantial influence on measurement accuracy. This presentation will highlight these key parameters and discuss ongoing developments aimed at enhancing the robustness of micro- and nanoplastic assessments.