Introduction to GC-MS Fragmentation and Interpretation

Thursday, June 19, 2025
8am PDT | 11am EDT | 4pm BST | 5pm CEST

In this webcast we explore the principles of fragmentation produced by electron impact ionization in GC-MS. This complex and often confusing topic is presented in a manner accessible to scientists of all abilities, covering the foundational knowledge required for anyone needing to increase their understanding of and confidence in the electron impact process and its relevance to National Institute of Standards and Technology library searching or structural interpretation of novel compounds.

Topics include:

  • A review of covalent bonding theory
  • Odd and even electron species
  • The electron impact process
  • Ionization site formation and stabilization
  • An introduction to charge retention and charge migration fragmentation mechanisms

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