CHROMtalks - A Plethora of Possibilities and Pitfalls for Sample Preparation in Gas Chromatography

Sample preparation for gas chromatographic analysis has benefitted immensely from the development of various microextraction techniques during the past two to three decades. Potential automation, high sensitivity, reduction or complete elimination of solvent usage and high throughput are among their most prominent advantages, having made these techniques a mainstay in sample preparation. On the other hand, the application of microextraction techniques requires a more stringent method development and optimization compared to liquid-based or macroscopic extraction techniques. This webcast discusses strategies to develop and optimize microextraction techniques to maximum performance, while at the same time avoiding common pitfalls with these techniques. Established and novel microextraction formats and materials will be discussed with a view to their practical applicability and relevant examples presented.

Topics include:

• Overview of microextraction techniques in GC sample preparation
• Key benefits: automation, high sensitivity, solvent reduction, and throughput
• Method development and optimization strategies
• Common pitfalls and how to avoid them
• Comparison with traditional liquid-based extraction techniques
• Established and emerging microextraction formats and materials
• Practical considerations and real-world application examples