HPLC Sustainability: Utilizing Advances in Column Technology to Develop Greener More Efficient Methods

Thursday, May 15, 2025
8am PDT | 11am EDT | 4pm BST | 5pm CEST

Chromatographers have a moral and commercial responsibility to reduce the environmental impact of our work in separation science. Amongst the 12 principles of Green Analytical Chemistry (GAC), reduction in solvent usage and waste is perhaps the easiest to achieve in High Performance Liquid Chromatography (HPLC) via reduced dimension columns and superficially porous chromatography media. This webcast explains the underlying theory, presents relevant worked examples and highlights the key strategies to ensure success in reducing solvent volume and the welcome reduction in purchase and disposal costs. The many associated benefits of reducing column dimensions and using high efficiency media are also explored, alongside a range of other tips and tricks to improve the green credentials of your HPLC methods.

Topics include:

• Explore the 12 principles of green analytical chemistry
• Understand the underlying theory which leads to successful separations using higher efficiency and reduced dimension chromatography columns
• Familiarize yourself with the practical approaches of translating or developing methods using higher efficiency and reduced dimension HPLC columns
• Avoid the potential pitfalls associated with translating and developing methods for high efficiency separations
• Understand the regulatory approach to method translation
• Explore the time and cost savings associated with high efficiency separations
• Appreciate a variety of ways in which further solvent savings may be made in HPLC analysis

Speaker

Emma Poole (Technical Business Development Specialist, Element Lab Solutions)