Why and When SEC-MALS is Needed

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0h 30m

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Discover why multi-angle light scattering (MALS) is an important addition to size exclusion chromatography (SEC) and when it provides advantages over conventional calibration. Learn when conventional calibration works, when it can be misleading, and how SEC-MALS provides true molecular weight and size measurements.

Explore examples where molecular size and structure matter, and understand when MALS can provide the additional information needed for more accurate macromolecular characterization.

 

Topics include:

  • Why is MALS needed?
  • When is MALS needed?
  • When conventional calibration (CC) works and when it does not
  • Distribution of true molecular weight and size from MALS
  • Examples where MALS is an advantage
  • Use of MALS when size and structure matter
Why and When SEC-MALS is Needed