CHROMtalks - The Role of Natural Deep Eutectic Solvents in Green Sample Prep Prior to LC-MS Analysis

Natural deep eutectic solvents (NADES) are emerging as sustainable alternatives to conventional organic solvents in sample preparation, aligning with Green Analytical Chemistry principles. Their biodegradable, non-toxic nature supports safer laboratory environments. Notably, the tunable composition of NADES allows for customized extraction systems tailored to specific analytes, enhancing selectivity and efficiency. This versatility makes them particularly effective in extracting compounds with diverse properties from complex food and environmental matrices. This presentation highlights their role in greener LC-MS-based workflows. This talk aims to showcase various applications of NADES, highlighting their multifunctional roles in the extraction of a wide range of compounds from food samples. Practical tips and advice will also be shared to support effective coupling of NADES with hyphenated techniques.