Introduction to LC-MS Data Interpretation

Following on from our Introduction to LC-MS Fragmentation webcast, this session explores how mass spectrometric data are interpreted to support the structural elucidation of unknown related substances.
Using a detailed worked example, we demonstrate how chromatographic, mass spectral, and fragmentation data are combined to build evidence for proposed chemical structures. Attendees will gain an understanding of the systematic approach used to evaluate analytical data and develop structural hypotheses for unknown impurities and related substances.

Topics include:
•    Reviewing key LC-MS fragmentation principles
•    Interpreting molecular ion and isotopic pattern information
•    Using fragmentation data to support structural assignments
•    Developing and evaluating structural hypotheses
•    Applying a systematic workflow to unknown related substances
•    Worked case study in LC-MS data interpretation

This webcast provides a practical introduction to the thought process and techniques used in LC-MS-based structural elucidation.