Skip to main content Skip to footer

Introduction to LC-MS Data Interpretation

Thursday, July 16, 2026
8am PDT | 11am EDT | 4pm BST | 5pm CEST

Following on from our Introduction to LC-MS Fragmentation webcast, this session explores how mass spectrometric data are interpreted to support the structural elucidation of unknown related substances.
Using a detailed worked example, we demonstrate how chromatographic, mass spectral, and fragmentation data are combined to build evidence for proposed chemical structures. Attendees will gain an understanding of the systematic approach used to evaluate analytical data and develop structural hypotheses for unknown impurities and related substances.

Topics include:
•    Reviewing key LC-MS fragmentation principles
•    Interpreting molecular ion and isotopic pattern information
•    Using fragmentation data to support structural assignments
•    Developing and evaluating structural hypotheses
•    Applying a systematic workflow to unknown related substances
•    Worked case study in LC-MS data interpretation

This webcast provides a practical introduction to the thought process and techniques used in LC-MS-based structural elucidation.

 

Speakers

 

Colin Towers (Senior Technical Support Chemist, Crawford Scientific)


After completing a degree in pharmacy, Colin pursued a career in analytical chemistry. Following three years performing routine testing and three years instrument maintenance and calibration, he moved into a role as a method development and validation specialist in contract research. Gaining 11 years’ experience in developing methods for HPLC, LC-MS, GC, GC-MS and SPE in a high throughput commercial environment, this was supplemented by three years lecturing in forensic analytical toxicology and a further three years working as a community pharmacist. Colin has now been with Crawford Scientific since 2011 as a technical specialist, consultant, and trainer.

Phil Aston (Technical and Training Consultant, Crawford Scientific)

 

Phil Aston is an experienced analytical chemist and training consultant with over 15 years of expertise spanning mass spectrometry, regulatory laboratories, and scientific education. As a Technical and Training Consultant at Crawford Scientific, he develops and delivers training across LC, GC, MS, and method development. Phil holds an M.Sc. in Instrumental and Analytical Methods on Biological and Environmental Chemistry from the University of Warwick and a B.Sc. in Biochemistry from the University of Manchester. His background includes more than eight years supporting academic mass spectrometry research, alongside practical experience in regulatory laboratories. Combining strong technical knowledge with an engaging training style, Phil is a trusted educator and advisor in the analytical sciences.

You are already a member of CHROMacademy.
Please sign in to pre-populate the form and register for the webcast.

You are already registered for this webcast.
Please sign in to enter the webcast lobby.

Complete this form to register for the webcast and receive free Lite membership to CHROMacademy

Already registered?

(* indicates required field)

If you are having trouble registering for or viewing this webcast, please contact us

Terms and conditions

By registering for this event, you agree to MJH Life Sciences® Terms and Conditions, Privacy Policy, and understand your data will be used by MJH and its affiliates for amongst other things, alerting you to other services or products that you may be interested in, and may be shared with or sold to third parties for their use, including possible contact with you through email or other communications, consistent with their respective privacy policy. If you do not agree to have your data used in this way, please contact [email protected]. By receiving FREE Lite membership to CHROMacademy, you agree to the CHROMacademy Terms and Conditions and Privacy Policy, as well as confirming you are OK with CHROMacademy emailing you about your membership and FREE to access content; including the CHROMacademy newsletter, webcasts, and promotions.