LC-MS Troubleshooting: From Frustration to Fix

Thursday, November 20, 2025
8am PDT | 11am EDT | 4pm GMT | 5pm CET

Liquid chromatography-mass spectrometry (LC-MS) is a powerful analytical tool that can deliver highly accurate and insightful data when running smoothly. But when problems arise, identifying the root cause can be daunting - even for experienced practitioners. This webcast will provide a structured approach to LC-MS troubleshooting, focusing on practical, real-world solutions that can help analysts quickly get back to generating reliable results.

Topics include:

  • Is it really the MS that’s at fault?
  • The need to control ionization
  • Calibration, calibration mixes, and compound tuning
  • Sensitivity issues
  • Selectivity vs. specificity
  • Precision issues

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