Maximizing Protein A Column Performance

Maximizing Protein A Column Performance, Lifetime, and Reliability Through Clean-in-Place

The useful lifetime of protein A analytical columns in bioprocessing applications can vary quite drastically depending on method conditions and sample composition. A common failure mode for such columns is fouling caused by the build-up of cell culture media components. This application note demonstrates how employing best practices can help mitigate these potential problems to realize the longest possible column lifetimes.

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